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BPS Bioscience的激酶篩選和檢測服務

提供商:BPSBioscience服務名稱:BPSBioscience的激酶篩選和檢測服務AccelerateyourdrugdiscoveryprogramwithKinaseScreeningandProfilingServicesfromBPSBioscience,Inc

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  • 廠商性質:生產廠家
  • 更新時間:2023-12-19
  • 訪  問  量:384
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詳細介紹
  • 提供商:

    BPS Bioscience

  • 服務名稱:

    BPS Bioscience的激酶篩選和檢測服務

Accelerate your drug discovery program with Kinase Screening and Profiling Services from BPS Bioscience, Inc. Trust us to provide you with high quality data with fast turnaround time. Our team of experts along with our broad services portfolio makes it easy to:

    • Screen for inhibitors/targets using our unique panel of 75+ assays

    • Select from IC50 determination and single point concentrations

    • Receive data within days of compound submission

    • Perform follow-up studies using the same proteins manufactured in-house

    • Get questions answered or project guidance in a time-efficient manner

圖片Biochemical Assays

Lipid:

PI3Kα (p110α/p85α)PI3Kβ (p110β/p85α)PI3Kδ (p110δ/p85α)PI3Kγ (p110γ/PIK3R5)
SPHK1

Tyrosine:

Ablc-SrcFGFR3(V443M)PDGFRα
Abl-1 (T315I)EGFR (WT)FGFR4PDGFRα(D842Y)
ALKEGFR (L858R)Flt1RET
ALK2EGFR (T790M)Flt3ROS1
AXLEGFR (L858R, T790M)FYNSYK
BTKEGFR(T790M, C797S,L858R) HER2TYK2
cKIT(D816V)EGFR (murine)HER4TYRO3
cKIT(V654A)EphA2Jak1VEGFR2/KDR
cMetEphB4Jak2(JH2)Yes1
cMet (exon 14 Del)FAKJak2(JH2)(V617F)
cMet (WT)FGFR2Jak3
cMerFGFR3(L496V)FGFR2
CSF1R(FMS)FGFR3(V443L)Lck

Serine-Threonine:

AKTCDK4/CyclinD1GSK3aPIM2
Aurora ACDK4/CyclinD3GSK3bPIM3
BRAFCDK5/p25HPK1/MAP4K1RIPK1
BRAF (V600E)CDK6/CyclinD3IKKβRIPK2
Casein Kinase 1CDK7/CyclinH1/
MNET1
MNK1TAK1-TAB1
CDK1/CyclinB1CDK9/CyclinT1p38TBK1
CDK2/CyclinA2CDK12/CyclinKPLK1TNIK
CDK2/CyclinE1cRAFPIM1TTK(Msp1)

Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.

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