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NY-ESO-1-Specific TCR Lentivirus (Clone c259)

保存條件:-80°C(dryice)保質(zhì)期:3-18month英文名:NY-ESO-1-SpecificTCRLentivirus(Clonec259)數(shù)量:1供應(yīng)商:BPSBioscienceInc

  • 產(chǎn)品型號(hào):
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時(shí)間:2023-10-11
  • 訪  問  量:390
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  • 保存條件:

    -80°C (dry ice)

  • 保質(zhì)期:

    3-18 month

  • 英文名:

    NY-ESO-1-Specific TCR Lentivirus (Clone c259)

  • 數(shù)量:

    1

  • 供應(yīng)商:

    BPS Bioscience Inc.

  • CAS號(hào):

    /

  • 規(guī)格:

    100 µl

The human NY-ESO-1-specific T Cell Receptor (TCR) lentiviruses (clone c259, also called α95:LY) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a human TCR (clone c259) that specifically recognizes antigen NY-ESO-1 (New York esophageal squamous cell carcinoma 1), and in which the TCR α chain and β chain are linked by P2A (Figure 1). The lentiviruses also transduce a puromycin selection gene. Figure 1. (A) Schematic of the lenti-vector used to generate the NY-ESO-1-specific TCR lentivirus and (B) Construct diagram showing expressed components of the NY-ESO-1-specific TCR.
TRAV and TRAC correspond to the TCR alpha chain variable and constant regions, respectively, whereas TRBV and TRBC correspond to the TCR beta chain variable and constant regions.
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