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PDE1B-HEK293 Recombinant Cell line

●Purchase●DescriptionRecombinantHEK293celllineexpressinghumanPDE1B(phosphodiesterase1B,accessionnumberNM_000924)

  • 產(chǎn)品型號:60402
  • 廠商性質(zhì):生產(chǎn)廠家
  • 更新時間:2023-11-11
  • 訪  問  量:205
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Description

Recombinant HEK293 cell line expressing human PDE1B (phosphodiesterase 1B, accession number NM_000924).

N-terminal His-tagged human PDE1B has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. The function of PDE1B was characterized by a cell-based cGMP assay. In this assay system, cells co-express atrial natriuretic peptide (ANP) receptor A (a guanylate cyclase), cyclic nucleotide5gated cation channel CNGA2, and the photoprotein aequorin. Intracellular cGMP level is monitored via aequorin luminescence induced by Ca2+ influx through CNGA2, acting as the intracellular cGMP sensor.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

Synonyms
PDE1B, phosphodiesterase 1B
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