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TGFβ-Responsive SBE Luciferase Reporter HEK293 Cell Line

  • 產(chǎn)品型號：60653
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2023-11-11
  • 訪  問  量：181
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Description

The transforming growth factor beta (TGFβ)-Responsive SBE Reporter HEK293 Cell Line contains a stably integrated Firefly luciferase gene under the control of SMAD-responsive elements (SMAD binding elements, SBE). This cell line monitors the activity of the TGFβ/SMAD Signaling Pathway.

It is activated in response to human TGFβ1 and to the agonist Activin A. Luciferase activity induced by human TGFβ1 is decreased by SB525334, an inhibitor of TGFβ1-receptor.

Figure 1: illustration of TGFβ/SMAD Signaling Pathway SBE Reporter HEK293 Cell Line.

This product has been cited 11 times.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

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Synonyms
SBE cell line, TGFbeta reporter, SMAD reporter, luciferase reporter, TGFβ, TGF-β, activin
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