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ARE Luciferase Reporter HepG2 Cell Line (Nrf2 Antioxidant Pathway)

●Purchase●DescriptionTheantioxidantresponseelement(ARE)LuciferaseReporterHepG2hepaticcelllinecontainsastablyintegratedfireflyluciferasereporterunderthecontrolofARE

  • 產(chǎn)品型號(hào)：60513
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2023-11-11
  • 訪  問(wèn)  量：280
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Description

The antioxidant response element (ARE) Luciferase Reporter HepG2 hepatic cell line contains a stably integrated firefly luciferase reporter under the control of ARE, which is recognized by the transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2). Luciferase expression correlates with activation of Nrf2 and the antioxidant pathway. This cell line was validated by stimulation with tert-butylhydroquinone, sulforaphane, and RTA-408 (omaveloxone).

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Figure 1: Illustration of the ARE Luciferase Reporter HepG2 Cell Line (Nrf2 Antioxidant Pathway) mechanism.

This product has been cited 31 times.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

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Synonyms
ARE cell line, Nrf2 reporter, Nrf, Hepg2, ARE
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