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●Purchase●DescriptionTheNF-κBreporter(Luc)-NIH-3T3celllineisdesignedformonitoringnuclearfactorKappaB(NF-κB)signaltransductionpathways
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The NF-κB reporter (Luc)-NIH-3T3 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.
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Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.
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